TRANSCRIPTION FACTORS INVOLVED IN CRANIOFACIAL AND LIMB CONGENITAL DISORDERS: IN-VIVO FUNCTIONAL STUDIES OF DLX AND T-BOX GENE FAMILIES

Pubblicazioni Scientifiche

• 2006 MECHANISMS OF DEVELOPMENT

  Msx1 and Dlx5 act independently in development of craniofacial skeleton, but converge on the regulation of Bmp signaling in palate formation

• 2001 HUMAN MOLECULAR GENETICS

  Connexin 31 (GJB3) is expressed in the peripheral and auditory nerves and causes neuropathy and hearing impairment

• 2001 INTERNATIONAL JOURNAL OF ONCOLOGY

  The coding region of the human DLX6 gene contains a polymorphic CAG/CCG repeat

• 2001 GENES & DEVELOPMENT

  Role of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer

• 2002 GENESIS

  Mouse model of split hand/foot malformation type I

• 2002 GENESIS

  Jaw transformation with gain of symmetry after Dlx5/Dlx6 inactivation: Mirror of the past?

• 2003 MOLECULAR AND CELLULAR NEUROSCIENCE

  The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse

• 2007 JOURNAL OF MOLECULAR HISTOLOGY

  The role of Dlx homeogenes in early development of the olfactory pathway

• 2011 JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

  A Symphony of Regulations Centered on p63 to Control Development of Ectoderm-Derived Structures

• 2004 MOLECULAR AND CELLULAR NEUROSCIENCE

  Defective neuronogenesis in the absence of Dlx5

• 2002 DEVELOPMENTAL BIOLOGY

  The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathway

• 2007 JOURNAL OF NEUROSCIENCE

  Activation of the Wnt-beta Catenin pathway in a cell population on the surface of the Forebrain is essential for the establishment of olfactory axon connections

• 2006 EUROPEAN JOURNAL OF MEDICAL GENETICS

  Novel TBX3 mutation data in families with Ulnar-Mammary syndrome indicate a genotype-phenotype relationship: mutations that do not disrupt the T-domain are associated with less severe limb defects

• 2008 DEVELOPMENT

  Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects