PRODUCTION OF AN IN VIVO CELLULAR MODEL OF FIBROUS DYSPLASIA OF BONE

Pubblicazioni Scientifiche

• 1999 CELL

  MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

• 2003 JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B

  Natural history and treatment of fibrous dysplasia of bone: a multicenter clinicopathologic study promoted by the European Pediatric Orthopaedic Society

• 2000 JOURNAL OF CLINICAL INVESTIGATION

  Marrow stromal stem cells

• 2002 DEVELOPMENT

  The meso-angioblast: a multipotent, self-renewing cell that originates from the dorsal aorta and differentiates into most mesodermal tissues

• 2001 JOURNAL OF CELL BIOLOGY

  Circulating skeletal stem cells

• 2000 JOURNAL OF CELLULAR BIOCHEMISTRY

  Osteogenic imprinting upstream of marrow stromal cell differentiation

• 2004 JOURNAL OF CELL BIOLOGY

  The interplay of osteogenesis and hematopoiesis: expression of a constitutively active PTH/PTHrP receptor in osteogenic cells perturbs the establishment of hematopoiesis in bone and of skeletal stem cells in the bone marrow

• 2002 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

  Characterization of gsp-mediated growth hormone excess in the context of McCune-Albright syndrome

• 1999 JOURNAL OF BONE AND MINERAL RESEARCH

  A novel GNAS1 mutation, R201G, in McCune-Albright syndrome

• 2001 JOURNAL OF BONE AND MINERAL RESEARCH

  Gnathodiaphyseal dysplasia: A syndrome of fibro-osseous lesions of jawbones, bone fragility, and long bone bowing

• 2003 JOURNAL OF BONE AND MINERAL RESEARCH

  Osteomalacic and hyperparathyroid changes in fibrous dysplasia of bone: Core biopsy studies and clinical correlations

• 2001 STEM CELLS

  Bone marrow stromal stem cells: Nature, biology, and potential applications

• 2003 CURRENT OPINION IN GENETICS & DEVELOPMENT

  Mesoangioblasts - vascular progenitors for extravascular mesodermal tissues

• 2004 Nucleic acids research

  A novel technique based on a PNA hybridization probe and FRET principle for quantification of mutant genotype in fibrous dysplasia/McCune-Albright syndrome

• 2003 JOURNAL OF CLINICAL INVESTIGATION

  FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting

• 2001 JOURNAL OF BONE AND MINERAL RESEARCH

  Renal phosphate wasting in fibrous dysplasia of bone is part of a generalized renal tubular dysfunction similar to that seen in tumor-induced osteomalacia

• 2001 JOURNAL OF BONE AND MINERAL RESEARCH

  Angiomatosis of bone with localized mineralization defect

• 2003 BONE

  Osteoclastogenesis in fibrous dysplasia of bone: in situ and in vitro analysis of IL-6 expression

• 2002 JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY

  An R201H activating mutation of the GNAS 1 (GsALPHA) gene in a corticotroph pituitary adenoma

• 2001 NATURE

  Stem cells in tissue engineering

• 2000 JOURNAL OF BONE AND MINERAL RESEARCH

  Mutations of the GNAS1 gene, stromal cell dysfunction, and osteomalacic changes in non-McCune-Albright fibrous dysplasia of bone