Emocromatosi: dai geni alla clinica e ritorno

Pubblicazioni Scientifiche

• 2013 HEMATOL-AM SOC HEMAT

  Iron and hepcidin: a story of recycling and balance

• 2015 Blood

  The second transferrin receptor regulates red blood cell production in mice

• 2015 HAEMATOLOGICA

  Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

• 2015 PLOS ONE

  Bmp6 Expression in Murine Liver Non Parenchymal Cells: A Mechanism to Control their High Iron Exporter Activity and Protect Hepatocytes from Iron Overload?

• 2013 PLOS ONE

  A Strong Anti-Inflammatory Signature Revealed by Liver Transcription Profiling of Tmprss6-/- Mice

• 2015 JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

  Identification of TMPRSS6 cleavage sites of hemojuvelin

• 2014 HUMAN MUTATION

  Functional and Clinical Impact of Novel Tmprss6 Variants in Iron-Refractory Iron-Deficiency Anemia Patients and Genotype-Phenotype Studies

• 2016 Blood

  Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice

• 2014 HAEMATOLOGICA

  The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice